Biomarker Reference · Cortisol-MD
Cortisol (midday) (Cortisol-MD) is a clinical biomarker used in adrenal-stress assessment. By midday cortisol secretion has begun its physiological decline from the morning peak. It is measured in 4 laboratory tests on BiomarkersLabs.com.
By midday cortisol secretion has begun its physiological decline from the morning peak. The slope of this decline reflects the integrity of central circadian regulation and negative feedback; a flat or inverted diurnal rhythm can signal chronic stress exposure, disrupted sleep-wake cycles, or autonomous hypersecretion.
A midday sample tracks the slope of the diurnal curve. Persistently elevated midday cortisol may indicate chronic stress or poor circadian rhythm; midday levels that remain high or fail to decline appropriately are a feature of some stress-related and mood disorders.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
4 tests on BiomarkersLabs.com include this biomarker.
Cortisol (midday) reference range in this test: Salivary cortisol typically 3–10 nmol/L; Ayumetrix-specific intervals apply.
Cortisol (midday) reference range in this test: Approximately 3–11 nmol/L in saliva; method- and time-specific.
Cortisol (midday) reference range in this test: Approximately 80–350 nmol/L (3–13 µg/dL) at midday.
Cortisol (midday) reference range in this test: Midday (12:00): approximately 80–350 nmol/L (3–13 µg/dL); values decline through the day.
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