Biomarker Reference · DGP-IgG
Deamidated Gliadin Peptide IgG Antibody (DGP-IgG) is a clinical biomarker used in gastrointestinal assessment. Deamidated gliadin peptides are generated by tissue transglutaminase and are more immunogenic than native gliadin. It is measured in 2 laboratory tests on BiomarkersLabs.com.
Deamidated gliadin peptides are generated by tissue transglutaminase and are more immunogenic than native gliadin. IgG antibodies to these peptides have improved sensitivity and specificity over older anti-gliadin tests and are particularly useful in IgA-deficient patients and in young children under two years, in whom IgA responses may be immature.
DGP-IgG complements tTG-IgA in two settings: as the primary serological marker in patients with selective IgA deficiency, and in very young children where both DGP-IgG and DGP-IgA may be positive before tTG-IgA becomes detectable. It is less specific than tTG-IgA in the general population, so interpretation must account for clinical context.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
2 tests on BiomarkersLabs.com include this biomarker.
Deamidated Gliadin Peptide IgG Antibody reference range in this test: <20 U/mL negative; ≥20 U/mL positive (assay-specific).
Deamidated Gliadin Peptide IgG Antibody reference range in this test: <20 U/mL negative; ≥20 U/mL positive (laboratory-specific thresholds).
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