Biomarker Reference · DA:NE
Dopamine to Norepinephrine Ratio (DA:NE) is a clinical biomarker used in neurological-mental-health assessment. This derived ratio reflects the balance between dopamine and its metabolic product norepinephrine in the periphery. It is measured in 1 laboratory test on BiomarkersLabs.com.
This derived ratio reflects the balance between dopamine and its metabolic product norepinephrine in the periphery. It may be influenced by the activity of dopamine beta-hydroxylase, the enzyme that converts dopamine to norepinephrine, and by adrenal versus sympathetic nerve contributions.
The DA:NE ratio is sometimes interpreted in functional medicine as a marker of enzymatic efficiency or sympathetic balance, but there is no peer-reviewed evidence linking this ratio to specific psychiatric diagnoses or treatment outcomes. It does not reflect central catecholamine metabolism.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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