What is Anti-SSB/La Antibody?
SSB/La antigen is a 48-kDa phosphoprotein that binds nascent RNA polymerase III transcripts. Anti-SSB/La is almost always accompanied by anti-SSA/Ro, so isolated anti-SSB/La is rare.
Biomarker Reference · Anti-SSB/La
Anti-SSB/La Antibody (Anti-SSB/La) is a clinical biomarker used in autoimmune-inflammation assessment. SSB/La antigen is a 48-kDa phosphoprotein that binds nascent RNA polymerase III transcripts. It is measured in 1 laboratory test on BiomarkersLabs.com.
SSB/La antigen is a 48-kDa phosphoprotein that binds nascent RNA polymerase III transcripts. Anti-SSB/La is almost always accompanied by anti-SSA/Ro, so isolated anti-SSB/La is rare.
Anti-SSB/La is found in 10–15 per cent of SLE patients and 40–50 per cent of those with Sjögren syndrome. Its presence alongside anti-SSA/Ro is associated with longer disease duration and more prominent sicca symptoms in Sjögren syndrome.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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