What is the reference range for Bicarbonate (Total CO2)?

The standard reference range for Bicarbonate (Total CO2) is Approximately 22–29 mmol/L (venous total CO2).. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Bicarbonate (Total CO2)?

Bicarbonate (Total CO2) is measured in 1 test on BiomarkersLabs.com, including Basic Metabolic Panel.

Biomarker Reference · CO2

What does the Bicarbonate (Total CO2) test measure?

Bicarbonate (Total CO2) (CO2) is a clinical biomarker used in metabolic-diabetes assessment. The total CO2 reported on a metabolic panel is predominantly serum bicarbonate, the metabolic component of acid-base balance regulated by the kidney. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Approximately 22–29 mmol/L (venous total CO2).
Units: mmol/L, mEq/L
Measured In: 1 test
Category: Metabolic

Functional medicine optimalMid-interval values; no established functional range distinct from the reference interval.

What is Bicarbonate (Total CO2)?

The total CO2 reported on a metabolic panel is predominantly serum bicarbonate, the metabolic component of acid-base balance regulated by the kidney. It falls when acid accumulates or bicarbonate is lost and rises with metabolic alkalosis or as renal compensation for chronic respiratory acidosis.

Why is Bicarbonate (Total CO2) measured?

Bicarbonate is the panel's window onto acid-base status. Read with chloride and the anion gap it distinguishes high-gap from normal-gap metabolic acidosis; read with potassium it helps explain transcellular shifts. A venous total CO2 is a screen rather than a substitute for arterial blood gas analysis when a precise acid-base assessment is required.

Reference ranges

Standard reference: Approximately 22–29 mmol/L (venous total CO2).
Functional medicine optimal: Mid-interval values; no established functional range distinct from the reference interval.
Units: mmol/L, mEq/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Bicarbonate (Total CO2)

1 test on BiomarkersLabs.com include this biomarker.

BML-MET-015Comprehensive

Basic Metabolic Panel

Bicarbonate (Total CO2) reference range in this test: Approximately 22–29 mmol/L (venous total CO2).

Related clinical conditions

Related Biomarkers

Frequently measured alongside

GlucoseGluc6 tests Calcium (Total)Ca4 tests SodiumNa6 tests PotassiumK6 tests ChlorideCl6 tests Blood Urea NitrogenBUN5 tests Serum CreatinineCr6 tests Estimated Glomerular Filtration RateeGFR6 tests

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