What is Estimated Glomerular Filtration Rate?
eGFR is not measured but computed from serum creatinine together with age and sex using a validated estimating equation (the race-free 2021 CKD-EPI creatinine equation in current practice). It converts a concentration into an estimate of filtering capacity standardised to body surface area, and inherits every limitation of creatinine — notably its dependence on muscle mass and its lag during rapidly changing function.