Biomarker Reference · Androgens

What does the DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone) test measure?

Q: What is the reference range for DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone)?

The standard reference range for DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone) is Sex- and method-specific dried-urine intervals # REVIEWER FLAG: Androgen-metabolite reference intervals are sex-specific and proprietary — reviewer to confirm against the laboratory's current intervals.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone) (Androgens) is a clinical biomarker used in adrenal-stress assessment. DHEA-S is the principal adrenal androgen precursor, while downstream androgens including testosterone are metabolised via 5-alpha and 5-beta pathways to androsterone and etiocholanolone, excreted in urine. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Sex- and method-specific dried-urine intervals # REVIEWER FLAG: Androgen-metabolite reference intervals are sex-specific and proprietary — reviewer to confirm against the laboratory's current intervals.
Units: ng/mg creatinine
Measured In: 1 test
Category: Adrenal

Functional medicine optimalSex- and context-specific; interpreted as a metabolic profile

What is DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone)?

DHEA-S is the principal adrenal androgen precursor, while downstream androgens including testosterone are metabolised via 5-alpha and 5-beta pathways to androsterone and etiocholanolone, excreted in urine. The relative activity of 5-alpha reductase, inferred from metabolite ratios, influences potent androgen exposure at tissue level. Dried urine captures these metabolites to profile androgen production and metabolism.

Why is DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone) measured?

Androgen and DHEA-S metabolites are used to assess adrenal androgen output and androgen metabolism in conditions such as PCOS, androgenic symptoms, and adrenal function assessment. The 5-alpha/5-beta metabolite balance is interpreted to gauge androgen activity. Findings inform functional assessment and are interpreted alongside serum measurements where definitive endocrine diagnosis is required.

Reference ranges

Standard reference: Sex- and method-specific dried-urine intervals # REVIEWER FLAG: Androgen-metabolite reference intervals are sex-specific and proprietary — reviewer to confirm against the laboratory's current intervals.
Functional medicine optimal: Sex- and context-specific; interpreted as a metabolic profile
Units: ng/mg creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone)

1 test on BiomarkersLabs.com include this biomarker.

BML-ADR-013Comprehensive

DUTCH Plus (Dried Urine Test for Comprehensive Hormones, Plus Salivary Cortisol Awakening Response)

DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone) reference range in this test: Sex- and method-specific dried-urine intervals # REVIEWER FLAG: Androgen-metabolite reference intervals are sex-specific and proprietary — reviewer to confirm against the laboratory's current intervals.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Free Cortisol Diurnal Pattern (Dried Urine)Free Cortisol1 test Cortisol Awakening ResponseCAR6 tests Cortisol Metabolites (a-Tetrahydrocortisol, b-Tetrahydrocortisol, Tetrahydrocortisone)Metabolised Cortisol1 test Oestrogen Metabolites (Oestrone, Oestradiol, Oestriol and 2-OH, 4-OH, 16-OH pathways)Oestrogens2 tests Progesterone Metabolites (a-Pregnanediol, b-Pregnanediol)Progesterone Metabolites2 tests Melatonin (6-Hydroxymelatonin Sulphate)6-OHMS1 test Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs)8-OHdG / OATs1 test

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