Biomarker Reference · 8-OHdG / OATs

What does the Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs) test measure?

Q: What is the reference range for Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs)?

The standard reference range for Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs) is Method-specific dried-urine intervals for each marker # REVIEWER FLAG: Organic-acid and 8-OHdG intervals are method-specific and the clinical utility of several OAT markers is debated — reviewer to confirm intervals and bound interpretive claims.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs) (8-OHdG / OATs) is a clinical biomarker used in adrenal-stress assessment. 8-Hydroxy-2-deoxyguanosine (8-OHdG) is a urinary marker of oxidative DNA damage. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Method-specific dried-urine intervals for each marker # REVIEWER FLAG: Organic-acid and 8-OHdG intervals are method-specific and the clinical utility of several OAT markers is debated — reviewer to confirm intervals and bound interpretive claims.
Units: ng/mg creatinine
Measured In: 1 test
Category: Adrenal

Functional medicine optimalLower oxidative-stress markers generally regarded as favourable; OATs interpreted as supportive context

What is Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs)?

8-Hydroxy-2-deoxyguanosine (8-OHdG) is a urinary marker of oxidative DNA damage. Selected organic acid markers reported alongside the hormone panel reflect aspects of neurotransmitter metabolism (such as dopamine and noradrenaline metabolites) and B-vitamin and glutathione-related pathways. These are measured from the same dried-urine specimen as adjunctive metabolic markers.

Why is Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs) measured?

8-OHdG is used as an indicator of systemic oxidative stress, and the organic acid markers are used adjunctively to flag possible nutrient or neurotransmitter-metabolism patterns for further evaluation. The clinical interpretation of several of these markers is not firmly established, so they are treated as supportive context rather than diagnostic findings.

Reference ranges

Standard reference: Method-specific dried-urine intervals for each marker # REVIEWER FLAG: Organic-acid and 8-OHdG intervals are method-specific and the clinical utility of several OAT markers is debated — reviewer to confirm intervals and bound interpretive claims.
Functional medicine optimal: Lower oxidative-stress markers generally regarded as favourable; OATs interpreted as supportive context
Units: ng/mg creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs)

1 test on BiomarkersLabs.com include this biomarker.

BML-ADR-013Comprehensive

DUTCH Plus (Dried Urine Test for Comprehensive Hormones, Plus Salivary Cortisol Awakening Response)

Oxidative Stress and Organic Acid Markers (8-OHdG and selected OATs) reference range in this test: Method-specific dried-urine intervals for each marker # REVIEWER FLAG: Organic-acid and 8-OHdG intervals are method-specific and the clinical utility of several OAT markers is debated — reviewer to confirm intervals and bound interpretive claims.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Free Cortisol Diurnal Pattern (Dried Urine)Free Cortisol1 test Cortisol Awakening ResponseCAR6 tests Cortisol Metabolites (a-Tetrahydrocortisol, b-Tetrahydrocortisol, Tetrahydrocortisone)Metabolised Cortisol1 test DHEA-S and Androgen Metabolites (Testosterone, 5a-DHT metabolites, Etiocholanolone, Androsterone)Androgens1 test Oestrogen Metabolites (Oestrone, Oestradiol, Oestriol and 2-OH, 4-OH, 16-OH pathways)Oestrogens2 tests Progesterone Metabolites (a-Pregnanediol, b-Pregnanediol)Progesterone Metabolites2 tests Melatonin (6-Hydroxymelatonin Sulphate)6-OHMS1 test

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