What is Inflammation and Immune Response Single Nucleotide Polymorphisms?
Cytokines such as interleukin-6, tumour necrosis factor alpha, and interleukin-1 beta mediate acute and chronic inflammation, while interleukin-10 exerts anti-inflammatory effects. Promoter and coding variants can shift the balance toward higher or lower cytokine production in response to infection, injury, or metabolic stress, influencing susceptibility to chronic inflammatory conditions.