Biomarker Reference · TP
Total Protein (TP) is a clinical biomarker used in metabolic-diabetes assessment. Total protein is the sum of albumin and globulins (immunoglobulins, acute-phase proteins, transport proteins, and others). It is measured in 3 laboratory tests on BiomarkersLabs.com.
Total protein is the sum of albumin and globulins (immunoglobulins, acute-phase proteins, transport proteins, and others). It provides a crude overview of protein nutritional status, hepatic synthetic function, and the presence of inflammation or monoclonal gammopathies. The albumin:globulin ratio (calculated as albumin divided by [total protein minus albumin]) helps interpret shifts.
Hypoproteinaemia (<6.0 g/dL) is seen with malnutrition, liver disease, nephrotic syndrome, and protein-losing states; it contributes to oedema. Hyperproteinaemia (>8.3 g/dL) can reflect dehydration or, if marked, a monoclonal protein (myeloma, MGUS); serum protein electrophoresis is the next step. The albumin:globulin ratio is typically 1.1–2.5; a low ratio suggests inflammation or immunoglobulin excess.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
3 tests on BiomarkersLabs.com include this biomarker.
Total Protein reference range in this test: 6.0–8.3 g/dL; sum of albumin and globulins.
Total Protein reference range in this test: 60–80 g/L (6.0–8.0 g/dL), laboratory-specific.
Total Protein reference range in this test: 6.0–8.3 g/dL (laboratory-specific).
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