Which tests measure Anti-SSA/Ro 60 kDa Antibody?

Anti-SSA/Ro 60 kDa Antibody is measured in 1 test on BiomarkersLabs.com, including ANA 11 Components (No ANA Screen).

Biomarker Reference · Anti-Ro60

What does the Anti-SSA/Ro 60 kDa Antibody test measure?

Q: Why is Anti-SSA/Ro 60 kDa Antibody measured?

Anti-Ro60 is the primary SSA marker for primary Sjögren's syndrome (present in 70–90% of cases) and is also found in SLE. It carries critical obstetric significance — maternal anti-Ro60 is associated with neonatal lupus erythematosus and congenital heart block, necessitating serial foetal cardiac surveillance by Doppler echocardiography from approximately 16 weeks of gestation in seropositive pregnancies.

Q: What is the reference range for Anti-SSA/Ro 60 kDa Antibody?

The standard reference range for Anti-SSA/Ro 60 kDa Antibody is <1.0 AI (negative); ≥1.0 AI (positive) # REVIEWER FLAG: Confirm with Access Med Labs whether Ro52 and Ro60 are reported on the same scale and whether the panel distinguishes them as separate components or reports a combined SSA result.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Anti-SSA/Ro 60 kDa Antibody (Anti-Ro60) is a clinical biomarker used in autoimmune-inflammation assessment. The Ro60 antigen is a cytoplasmic and nuclear RNA-binding protein involved in RNA quality control and surveillance of misfolded non-coding RNAs. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: <1.0 AI (negative); ≥1.0 AI (positive) # REVIEWER FLAG: Confirm with Access Med Labs whether Ro52 and Ro60 are reported on the same scale and whether the panel distinguishes them as separate components or reports a combined SSA result.
Units: AI (antibody index)
Measured In: 1 test
Category: Autoimmune

Functional medicine optimalNegative — positive result in pregnancy requires obstetric referral for foetal cardiac monitoring regardless of titre level.

What is Anti-SSA/Ro 60 kDa Antibody?

The Ro60 antigen is a cytoplasmic and nuclear RNA-binding protein involved in RNA quality control and surveillance of misfolded non-coding RNAs. Anti-Ro60 antibodies are among the most prevalent autoantibodies in systemic autoimmune rheumatic disease and can cross the placenta with direct foetal consequences.

Why is Anti-SSA/Ro 60 kDa Antibody measured?

Anti-Ro60 is the primary SSA marker for primary Sjögren's syndrome (present in 70–90% of cases) and is also found in SLE. It carries critical obstetric significance — maternal anti-Ro60 is associated with neonatal lupus erythematosus and congenital heart block, necessitating serial foetal cardiac surveillance by Doppler echocardiography from approximately 16 weeks of gestation in seropositive pregnancies.

Reference ranges

Standard reference: <1.0 AI (negative); ≥1.0 AI (positive) # REVIEWER FLAG: Confirm with Access Med Labs whether Ro52 and Ro60 are reported on the same scale and whether the panel distinguishes them as separate components or reports a combined SSA result.
Functional medicine optimal: Negative — positive result in pregnancy requires obstetric referral for foetal cardiac monitoring regardless of titre level.
Units: AI (antibody index)

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Anti-SSA/Ro 60 kDa Antibody

1 test on BiomarkersLabs.com include this biomarker.

BML-AUT-001Comprehensive

ANA 11 Components (No ANA Screen)

Anti-SSA/Ro 60 kDa Antibody reference range in this test: <1.0 AI (negative); ≥1.0 AI (positive) # REVIEWER FLAG: Confirm with Access Med Labs whether Ro52 and Ro60 are reported on the same scale and whether the panel distinguishes them as separate components or reports a combined SSA result.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Anti-Double-Stranded DNA Antibody (IgG)Anti-dsDNA IgG1 test Anti-Smith AntibodyAnti-Sm1 test Anti-U1 Ribonucleoprotein AntibodyAnti-RNP1 test Anti-SSA/Ro 52 kDa Antibody (TRIM21)Anti-Ro521 test Anti-SSB/La AntibodyAnti-La1 test Anti-Scl-70 (Topoisomerase I) AntibodyAnti-Scl-701 test Anti-Jo-1 (Histidyl-tRNA Synthetase) AntibodyAnti-Jo-11 test Anti-Centromere B AntibodyAnti-CENP-B1 test

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