Biomarker Reference · DHEA
Dehydroepiandrosterone (DHEA) is a clinical biomarker used in adrenal-stress assessment. Dehydroepiandrosterone is the principal C19 steroid secreted by the zona reticularis of the adrenal cortex and a precursor for peripheral androgen and oestrogen synthesis. It is measured in 4 laboratory tests on BiomarkersLabs.com.
Dehydroepiandrosterone is the principal C19 steroid secreted by the zona reticularis of the adrenal cortex and a precursor for peripheral androgen and oestrogen synthesis. DHEA (and its sulphated form DHEAS in serum) peak in early adulthood and decline progressively with age. Salivary DHEA reflects free, unconjugated hormone.
DHEA is often framed as a counterbalance to cortisol — it has anabolic, neuroprotective, and immune-supporting properties. A low DHEA relative to cortisol is interpreted in functional practice as a sign of adrenal reserve depletion, though the cortisol:DHEA ratio is not standardised in conventional endocrinology. DHEA supplementation is common in integrative settings; monitoring levels guides dosing.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
4 tests on BiomarkersLabs.com include this biomarker.
Dehydroepiandrosterone reference range in this test: Approximately 0.3–3.5 ng/mL in saliva; highly age- and sex-dependent.
Dehydroepiandrosterone reference range in this test: Dried urine: varies by age and sex; proprietary method-specific intervals.
Dehydroepiandrosterone reference range in this test: Women 20–200 ng/mg creatinine, age-dependent decline.
Dehydroepiandrosterone reference range in this test: Age- and sex-dependent; adults typically 100–600 ng/mg creatinine.
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