Which tests measure Dopamine, 24-Hour Urine?

Dopamine, 24-Hour Urine is measured in 1 test on BiomarkersLabs.com, including NeuroBasic Profile — 24 Hour Urine.

Biomarker Reference · DA

What does the Dopamine, 24-Hour Urine test measure?

Q: What is the reference range for Dopamine, 24-Hour Urine?

The standard reference range for Dopamine, 24-Hour Urine is 52–480 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range — catecholamine reference intervals are sensitive to collection protocol and patient demographics.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Dopamine, 24-Hour Urine (DA) is a clinical biomarker used in neurological-mental-health assessment. Dopamine is synthesised from L-tyrosine via L-DOPA through the sequential actions of tyrosine hydroxylase and DOPA decarboxylase. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: 52–480 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range — catecholamine reference intervals are sensitive to collection protocol and patient demographics.
Units: µg/24h, nmol/24h
Measured In: 1 test
Category: Neurological

Functional medicine optimalFunctional medicine protocols typically target mid-reference range; no standardised optimal threshold exists. # REVIEWER FLAG: Confirm Doctor's Data documentation for functional range guidance.

What is Dopamine, 24-Hour Urine?

Dopamine is synthesised from L-tyrosine via L-DOPA through the sequential actions of tyrosine hydroxylase and DOPA decarboxylase. In urine, dopamine derives from renal tubular cells (which synthesise and excrete dopamine locally), peripheral sympathetic neurons, the adrenal medulla, and intestinal enteroendocrine cells. Central dopaminergic neurons contribute negligibly to urinary dopamine levels given the blood-brain barrier. Dopamine is catabolised to homovanillic acid (HVA) via COMT and MAO pathways.

Why is Dopamine, 24-Hour Urine measured?

Urinary dopamine is used in functional medicine assessments of dopaminergic activity, motivation, and focus, and as a guide for amino acid precursor therapy with L-tyrosine or L-phenylalanine. Elevated levels are clinically relevant in the investigation of catecholamine-secreting tumours (phaeochromocytoma, paraganglioma), where 24-hour urine catecholamines are a standard diagnostic tool. Practitioners should recognise that urinary dopamine reflects peripheral production and is not a validated surrogate for mesolimbic or nigrostriatal dopaminergic neurotransmission.

Reference ranges

Standard reference: 52–480 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range — catecholamine reference intervals are sensitive to collection protocol and patient demographics.
Functional medicine optimal: Functional medicine protocols typically target mid-reference range; no standardised optimal threshold exists. # REVIEWER FLAG: Confirm Doctor's Data documentation for functional range guidance.
Units: µg/24h, nmol/24h

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Dopamine, 24-Hour Urine

1 test on BiomarkersLabs.com include this biomarker.

BML-NMH-001Comprehensive

NeuroBasic Profile — 24 Hour Urine

Dopamine, 24-Hour Urine reference range in this test: 52–480 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range — catecholamine reference intervals are sensitive to collection protocol and patient demographics.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Serotonin (5-Hydroxytryptamine), 24-Hour Urine5-HT1 test Norepinephrine (Noradrenaline), 24-Hour UrineNE1 test Epinephrine (Adrenaline), 24-Hour UrineEPI1 test GABA (γ-Aminobutyric Acid), 24-Hour UrineGABA1 test Glutamate, 24-Hour UrineGlu1 test Glycine, 24-Hour UrineGly1 test β-Phenylethylamine (PEA), 24-Hour UrinePEA1 test Histamine, 24-Hour UrineHist1 test

Order tests measuring Dopamine, 24-Hour Urine for your patients

Available exclusively to verified licensed healthcare practitioners. CLIA-certified and IVDR-compliant laboratory results delivered to your secure portal.