What is the reference range for Epinephrine (Adrenaline), 24-Hour Urine?

The standard reference range for Epinephrine (Adrenaline), 24-Hour Urine is 1.7–22.4 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Epinephrine (Adrenaline), 24-Hour Urine?

Epinephrine (Adrenaline), 24-Hour Urine is measured in 1 test on BiomarkersLabs.com, including NeuroBasic Profile — 24 Hour Urine.

Biomarker Reference · EPI

What does the Epinephrine (Adrenaline), 24-Hour Urine test measure?

Epinephrine (Adrenaline), 24-Hour Urine (EPI) is a clinical biomarker used in neurological-mental-health assessment. Epinephrine is synthesised exclusively in the adrenal medulla from norepinephrine by phenylethanolamine-N-methyltransferase (PNMT), a reaction induced by high local cortisol concentrations from the adrenal cortex. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: 1.7–22.4 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range.
Units: µg/24h, nmol/24h
Measured In: 1 test
Category: Neurological

Functional medicine optimalNo standardised functional medicine optimal range. # REVIEWER FLAG: Confirm Doctor's Data documentation.

What is Epinephrine (Adrenaline), 24-Hour Urine?

Epinephrine is synthesised exclusively in the adrenal medulla from norepinephrine by phenylethanolamine-N-methyltransferase (PNMT), a reaction induced by high local cortisol concentrations from the adrenal cortex. Its urinary output reflects adrenomedullary secretory activity rather than peripheral sympathetic neuronal function, distinguishing it mechanistically from norepinephrine in clinical interpretation.

Why is Epinephrine (Adrenaline), 24-Hour Urine measured?

Urinary epinephrine is assessed as a direct marker of adrenomedullary output. In functional medicine, chronically suppressed epinephrine output alongside low norepinephrine is interpreted as evidence of adrenal medullary depletion in the context of prolonged sympathetic activation. As with norepinephrine, significantly elevated values warrant formal investigation to exclude phaeochromocytoma before functional interpretations are applied.

Reference ranges

Standard reference: 1.7–22.4 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range.
Functional medicine optimal: No standardised functional medicine optimal range. # REVIEWER FLAG: Confirm Doctor's Data documentation.
Units: µg/24h, nmol/24h

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Epinephrine (Adrenaline), 24-Hour Urine

1 test on BiomarkersLabs.com include this biomarker.

BML-NMH-001Comprehensive

NeuroBasic Profile — 24 Hour Urine

Epinephrine (Adrenaline), 24-Hour Urine reference range in this test: 1.7–22.4 µg/24h # REVIEWER FLAG: Confirm Doctor's Data reference range.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Serotonin (5-Hydroxytryptamine), 24-Hour Urine5-HT1 test Dopamine, 24-Hour UrineDA1 test Norepinephrine (Noradrenaline), 24-Hour UrineNE1 test GABA (γ-Aminobutyric Acid), 24-Hour UrineGABA1 test Glutamate, 24-Hour UrineGlu1 test Glycine, 24-Hour UrineGly1 test β-Phenylethylamine (PEA), 24-Hour UrinePEA1 test Histamine, 24-Hour UrineHist1 test

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