What is Glycine, 24-Hour Urine?
Glycine serves dual roles as an inhibitory neurotransmitter — acting at glycine receptors in the spinal cord and brainstem — and as a major component of collagen, glutathione synthesis, and one-carbon metabolism. Urinary glycine reflects a combination of protein catabolism, hepatic glycine conjugation, and renal tubular handling rather than central glycinergic neurotransmission directly.