What does the Nickel (Urine) test measure?

Why is Nickel (Urine) measured?

Elevated urinary nickel suggests increased intake or occupational exposure. Nickel hypersensitivity (contact dermatitis) is common but is a cell-mediated allergic response, not dependent on systemic nickel load. Systemic nickel allergy syndrome is debated. Interpret elevations with occupational and dietary history.

Reference ranges

Standard reference

<3 µg/g creatinine

Functional medicine optimal

<2 µg/g creatinine outside occupational exposure.

Units

µg/g creatinine, µg/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.