What is 2-Hydroxyestradiol?
2-Hydroxyestradiol is the 2-hydroxylated metabolite of oestradiol, formed by the same CYP enzymes that hydroxylate oestrone. It contributes to the overall 2-hydroxylation pathway.
Biomarker Reference · 2-OHE2
2-Hydroxyestradiol (2-OHE2) is a clinical biomarker used in thyroid-endocrine assessment. 2-Hydroxyestradiol is the 2-hydroxylated metabolite of oestradiol, formed by the same CYP enzymes that hydroxylate oestrone. It is measured in 2 laboratory tests on BiomarkersLabs.com.
2-Hydroxyestradiol is the 2-hydroxylated metabolite of oestradiol, formed by the same CYP enzymes that hydroxylate oestrone. It contributes to the overall 2-hydroxylation pathway.
In functional oestrogen metabolism profiles 2-OHE2 is grouped with 2-OHE1 as a 'protective' metabolite. There is no established clinical use for this measurement outside functional practice.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
2 tests on BiomarkersLabs.com include this biomarker.
2-Hydroxyestradiol reference range in this test: Dried urine: proprietary method-specific intervals; no consensus clinical reference.
2-Hydroxyestradiol reference range in this test: Typically 0.5–4 ng/mg creatinine.
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