What does the Aflatoxins (B1, G1, G2, M1), Urine test measure?

Why is Aflatoxins (B1, G1, G2, M1), Urine measured?

Urinary aflatoxin detection — particularly AFM1 — provides direct evidence of recent dietary aflatoxin exposure from contaminated peanut products, corn, tree nuts, or dried spices. Elevated urinary aflatoxins in functional medicine assessments are associated with hepatotoxic risk, immunosuppression, and — at sustained high exposures — hepatocellular carcinoma risk in combination with hepatitis B infection. Exposure source identification is the primary clinical action — dietary review and source elimination are the intervention priorities. Water-damaged building exposure as a source of aflatoxin is less common than dietary exposure in North American populations; food-sourced aflatoxin exposure through contaminated staple grains is predominantly a concern in sub-Saharan Africa, Southeast Asia, and agricultural communities with poor grain storage.

Reference ranges

Standard reference

# REVIEWER FLAG: Confirm Mosaic Diagnostics reference ranges for individual aflatoxin species — confirm whether all four aflatoxin metabolites are measured discretely or whether a combined aflatoxin value is reported. Aflatoxin M1 is the hydroxylated metabolite of AFB1 and the primary urinary biomarker of aflatoxin B1 exposure; confirm whether AFM1 is the primary aflatoxin analyte in the urinary panel.

Functional medicine optimal

# REVIEWER FLAG: Confirm Mosaic Diagnostics' clinical interpretive zones for aflatoxins.

Units

ppb (µg/L), ng/g creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.