What does the Trichothecenes — Type A and Type B (including Satratoxins, Roridins, Verrucarin, Deoxynivalenol, T-2 Toxin), Urine test measure?

Why is Trichothecenes — Type A and Type B (including Satratoxins, Roridins, Verrucarin, Deoxynivalenol, T-2 Toxin), Urine measured?

Trichothecene detection in urinary mycotoxin panels has distinct interpretive implications depending on the class. Type B trichothecenes — particularly deoxynivalenol (DON, 'vomitoxin') — are widespread dietary contaminants of wheat, barley, and oats consumed by humans, and low-level urinary DON detection in the general population reflects common dietary exposure rather than pathological building mould exposure. Macrocyclic trichothecenes from Stachybotrys (satratoxins, roridins, verrucarin) are not present in the food supply and their detection in urine is a specific indicator of exposure to water-damaged building environments harbouring Stachybotrys chartarum. Elevated macrocyclic trichothecenes in a symptomatic patient are one of the most clinically significant findings in the MycoTOX panel, warranting environmental assessment of the patient's home or workplace. # REVIEWER FLAG: The clinical evidence base for urinary trichothecene measurement as a diagnostic biomarker for Stachybotrys-related building illness is debated in mainstream occupational and environmental medicine — reviewer to confirm appropriate interpretive framing for this platform's practitioner audience.

Reference ranges

Standard reference

# REVIEWER FLAG: Confirm the specific trichothecene analytes measured by Mosaic Diagnostics in the MycoTOX Profile — the panel is known to include both Type A (T-2, HT-2, Diacetoxyscirpenol) and Type B (deoxynivalenol, DON; nivalenol) trichothecenes, plus the macrocyclic trichothecenes (Satratoxin G, Satratoxin H, Roridin A, Roridin E, Roridin H, Roridin L-2, Verrucarin A, Verrucarin J) that are specifically produced by Stachybotrys chartarum (black mould). Confirm which trichothecene analytes are discretely reported and their individual reference ranges.

Functional medicine optimal

# REVIEWER FLAG: Confirm Mosaic Diagnostics' interpretive zones — the clinical significance of macrocyclic trichothecene detection vs dietary Type B trichothecene detection should be clearly differentiated in interpretive thresholds.

Units

ppb (µg/L), ng/g creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.